India's BSE Sensex falls 0.26 percent, while the NSE Nifty falls 0.4 percent, off highs on profit-taking after the NSE stock futures breached the key psychological level of 6,000 for the first time since Jan. 7, 2011.
Traders also cite renewed concerns about India's current account deficit after data on Tuesday showed exports fell 4 percent to $22.3 billion in November, while imports jumped to $41.5 billion, leaving a trade deficit of $19.3 billion.
Traders focused on the outcome of factory data on Wednesday and inflation data on Friday, which are coming ahead of RBI's rate-setting meet on Dec. 18.
Rate sensitive stocks come under pressure: State Bank of India falls 1 percent, Tata Motors falls 1.4 percent.
TCS shares down 0.9 percent have fallen 6.04 percent in past 5 sessions on outlook concerns.