San Antonio, United States:
Concepts, Inc. has announced that ABThera™ Open Abdomen
Negative Pressure Therapy System (ABThera™ OA NPT) was
associated with a significantly higher ultimate midline fascial closure
rate compared to traditional Barker vacuum pack technique (BVPT)
according to a new retrospective study published in the Journal of the
American College of Surgeons.1 Improved patient
results and savings from successful closure offset the added cost of the
negative pressure device, according to the study authors.
“My bias going into this study was that there would be no difference in
outcomes between the two techniques,” said Richard C. Frazee, MD, FACS,
Vice Chairman Surgical Services, Scott & White Hospital, and lead author
of the study. “However, the study showed a clear advantage favoring the
ABThera™ OA NPT, and we continue to use it for our open
abdomen patients with good success.”
Leaving the abdomen open during the management of complex abdominal
problems has become common practice. A prolonged open abdomen can result
in fluid loss, infection, loss of abdominal domain, organ dysfunction
and death. Clinical research has shown that removing potentially
detrimental peritoneal fluid and achieving primary fascial closure are
important goals when managing patients who require an open abdomen for
the treatment of critical illness.2 The methods of temporary
abdominal closure (TAC) chosen may play an important role in patient
In this study, 37 open abdomen patients who had temporary abdominal
closure with ABThera™ OA NPT from 2010 to 2011 were compared
to 37 patients using BVPT for open abdomen management from 2009 to 2010.
This study analyzed patient demographics, body mass index (BMI),
preoperative albumin, indication for open abdomen management, number of
operations, use of sequential closure and success with closure. Although
the initial up-front cost of the ABThera™ OA NPT was higher
than that of BVPT, the authors suggest that ABThera™ OA NPT
was associated with potential significant cost savings due to a
reduction of long-term morbidity and subsequent ventral hernia repair.
In 33 patients (89 percent), ultimate midline fascial closure was
achieved with the ABThera™ OA NPT group versus 22
patients (59 percent) using BVPT (p< 0.05). Based on the difference in
closure rates between these two methods, the authors estimated that 11
ventral hernias could have been prevented for a cost savings of $176,000.
“KCI is committed to changing the practice of medicine and improving
patient lives,” said Ron Silverman, MD, chief medical officer, KCI. “The
clinical results and health economic implications of this important
study should prove very helpful to clinicians managing patients with an
open abdomen, which is a complex and often life-threatening condition.”
The ABThera™ Open Abdomen Negative Pressure Therapy
System is indicated for temporary bridging of abdominal wall openings
where primary closure is not possible and repeat abdominal entries are
necessary. This system is intended for use in open abdominal wounds with
exposed viscera, including, but not limited to, abdominal compartment
For more information or to download the article, please visit www.abthera.com.
Kinetic Concepts, Inc. is a leading global medical technology company
devoted to the discovery, development, manufacture and marketing of
innovative, high-technology therapies and products for the wound care
and therapeutic support system markets. Headquartered in San Antonio,
Texas, KCI has significantly advanced the science of wound healing over
the course of more than three decades. KCI success can be traced to a
history deeply rooted in innovation and a passion for significantly
improving patient outcomes while reducing the overall cost of care for
patients around the world. Proprietary KCI negative pressure
technologies have revolutionized the way in which caregivers treat a
wide variety of wound types. Additional information about KCI and its
products is available at www.KCI1.com.
1Frazee RC, Abernathy SW, Jupiter DC, et al. Are Commercial
Negative Pressure Systems Worth the Cost in Open Abdomen Management? J
Am Coll Surg 2013:1-4 (in press).
2Goussos N, Kim BD, Jenkins DH, et al. Factors affecting
primary fascial closure of the open abdomen in the nontrauma patient.
Surgery 2012 October 1;152(4):777-84.
KCI Corporate Communications
Mike Barger, 1-210-255-6825