The Kerala-born Catherine grew up in Dubai. She moved to Bangalore and turned to modelling. She has done ads for leading textile and jewellery stores and made her debut in Kannada opposite Upendra in Godfather and Vijay in Shankar IPS . In Malayalam Catherine has acted in The Thriller and Uppukundam Brothers.
Catherine Tresa plays second lead with Allu Arjun in Puri Jagannath directed, Iddarammayilatho. In Tamil, she is in talks with directors and will soon make her debut in Kollywood.