"He is 'The One,'" said Oprah Winfrey, his biggest and most influential celebrity champion.
"The best candidate I've ever seen," said George Clooney.
Halle Berry said she'd "collect paper cups off the ground to make his pathway clear." Black Eyed Peas frontman will.i.am chimed in with the famous Yes We Can video.
But you can't be the Next Big Thing twice and as a new election year dawns, there's clearly a different mood in heavily Democratic Hollywood.
Text: Jocelyn Noveck/Associated Press