Nearly 50 children were killed in Egypt when a speeding train ploughed into a school bus carrying children.
Several more were also wounded in the crash on Saturday that happened as the bus crossed rail tracks in Manfaloot district in the southern province of Assiut, 300km south of Cairo.
Mohamed Rashad, the transport minister, and the head of the railways authority submitted their resignations, following the incident.
Egyptian President Mohamed Morsi pledged to hold those responsible to account and ordered the the government "to offer all the assistance to the families of the victims", state media said.
As per preliminary reports, a guard responsible for monitoring the crossing fell asleep, leaving it open.