Prime Minister Manmohan Singh: "This is a dastardly attack, the guilty will not go unpunished," the PM tweeted.
"I appeal to the public to remain calm and maintain peace," Singh said.
Union Home Minister Sushilkumar Shinde admitted the government had received intelligence warning of blasts taking place in the country but no specific target was mentioned.
"We were receiving information for the last two days that such a blast may take place... there was no input about which city would be targeted," Shinde told reporters adding that the information was passed onto all the states.
"We cannot speculate about the perpetrators at this point of time," he said further.
Congress chief Sonia Gandhi expressed her sorrow by issuing a statement.
"Sonia Gandhi has expressed her sorrow and anguish on the blasts in Hyderabad," said the statement.
Asking people to not to believe in rumours, MIM leader Asaduddin Owaisi said that peace should not be disturbed and people should follow good sense. "I strongly condemn this inhuman and barbaric act. Many innocents have lost their lives," he said.
Investigating agencies, he said, should do a professional job and find out who were the real perpetrators of such heinous crime.
He also assured the government of all the help from his party in maintaining peace.
Information and Broadcasting Minister Manish Tewari said the government strongly condemned the dastardly act.
"We strongly condemn it and our sympathies are with the victims and families," he said.
Chief Minister N Kiran Kumar Reddy rushed the spot of the blasts today and described the attack as an "act of cowards".
"We condemn this barbaric act. The state government along with central government will see to it that the culprits are booked as early as possible," he said.
"We condemn this act of terrorism on innocent people. This is only to disturb peaceful living of all communities in Hyderabad and Andhra Pradesh," he said while appealing to people to maintain peace.
Union Home Secretary R K Singh said a NSG team headed for Hyderabad from Delhi by a BSF aircraft. A team of NIA hub stationed in Hyderabad has also rushed to the spot. Singh said the near two simultaneous very powerful blasts indicate that it was a "terror attack".
Singh said no group has taken responsibility yet.
State DGP Dinesh Reddy said it was "definitely the handiwork of a terrorist network." Reddy said IEDs were used in the attack.
Lok Sabha Speaker Meira Kumar condoled the loss of lives in the blasts and conveyed her condolences to the bereaved families.
Tourism Minister K Chiranjeevi condemned the blasts in Hyderabad and extended his heartfelt condolences to the bereaved families. He asked Andhra Pradesh Chief Minister K Kiran Kumar Reddy to conduct a thorough inquiry into the incident and take action against those guilty.
Gujarat Chief Minister Narendra Modi said the news of blasts in Hyderabad was saddening.
"News of blasts in Hyderabad is saddening. My condolences to the families of those who lost their lives. Praying for peace & calm there," Modi tweeted.
President Pranab Mukherjee strongly condemned the twin blasts in Hyderabad and said these were "acts of cowardice" to disrupt peace and harmony in the country.
Expressing his condolences to families of the bereaved, he called for zero-tolerance against such acts and asked people to maintain calm in wake of such incidents.
Terming the Hyderabad bomb blasts "unfortunate", Bharatiya Janata Party president Rajnath Singh sought a "comprehensive" investigation into the incident.
"This is a very sad and unfortunate incident and I believe it is a constant challenge presented to the country by terrorists. There should be a comprehensive investigation," he said.
"I have faith that the government will ensure proper arrangements for the injured. I express my condolence over the whole incident and share my grief with the family of victims," he told reporters.
BJP state president G Kishan Reddy said communal harmony should prevail.
"Our immediate concern is to see that the injured persons get better treatment. We want communal harmony to prevail," Kishan said.
Hyderabad Mayor Md Majid Hussain said it was an "act of cowardice".
"Whoever has done this...it is a cowardly act. I strongly condemn it," he told reporters after visiting the scene of the blasts in which 11 people were killed.
The mayor said it was time for everyone to stand united and fight such cowardly acts. "This is a moment of deep grief and I extend my sympathy to the bereaved families," he added.