Former No. 1 Lleyton Hewitt of Australia and fifth-seeded Andreas Seppi of Italy lost Monday in the first round of the Nice Open.
Hewitt, playing in this tournament for the first time, was beaten by Pablo Andujar of Spain 6-3, 4-6, 6-3. Seppi fell to Lu Yen-Hsun of Taiwan 7-5, 1-6, 6-4. Lu will next play Andujar, a semifinalist at this month's Madrid Open.
Carlos Berlocq of Argentina and Robin Haase of the Netherlands also advanced. Haase faces fourth-seeded John Isner of the U.S. in the next round.
Berlocq didn't face a break point in his 6-2, 6-1 victory over compatriot Leonardo Mayer. Haase beat Marinko Matosevic of Australia 6-1, 6-4.