# Now, a mathematical formula to help marathoners sprint to a strong finish

Last Updated: Fri, Oct 22, 2010 06:40 hrs

A marathoner from the Harvard-MIT Division of Health Sciences and Technology has designed a mathematical model to calculate just how much carbohydrate a runner needs to fuel him or herself through 26.2 miles, and what pace that runner can reasonably expect to sustain.

Benjamin Rapoport once experienced a common phenomenon among marathoners, known as "hitting the wall." Essentially, the body runs out of fuel, forcing the runner to slow down dramatically.

"It's a big psychological letdown, because you feel powerless. You can't will yourself to run any faster," said Rapoport.

Hitting the wall occurs when stored carbohydrates are completely depleted, forcing the body to start burning fat. When that happens, the runner's pace can drop about 30 percent, and ketones, the byproducts of fat metabolism, start building up in the body, causing pain and fatigue.

"In order to avoid it, you need to know what your capabilities are. You need to set a target pace that will get you to the finish without hitting the wall. Once you do that, you need to make sure you appropriately carbo-load," said Rapoport.

To create his new model, Rapoport identified two fundamental physiologic factors that limit performance in endurance runners: aerobic capacity, also known as VO2max, and the ability of the leg muscles to store carbohydrates as glycogen.

The model's predictions also depend on the runner's leg muscle mass, because larger muscles can store more glycogen. Rapoport's model also allows runners to calculate how much carbohydrate they need to consume during the race if they want to run a faster pace without hitting the wall.

A VO2max of 60 ml/kg/min is about the highest that most men can attain through training, and 3:10 happens to be a gold standard in marathoning. For women of the same age, the qualifying time is 3:40, which is also the time that Rapoport's model predicts for a runner with a VO2max of 52 ml/kg/min, about the highest level the average woman can attain through training.

One of the most important things a runner should do during a marathon is stick to his or her target pace, Rapoport advised. When runners start out too fast, they burn a higher percentage of carbohydrates, increasing the risk of hitting the wall.

"People sometimes get too excited or change their game plan on the day of the race, and that's a tactical mistake."

The model is described in the Oct. 21 issue of the journal PLoS Computational Biology. (ANI)