Dayan Viciedo doubled home the go-ahead run in the ninth inning and the Chicago White Sox rallied to beat the Toronto Blue Jays 4-3 on Tuesday.
Paul Konerko hit a game-tying homer and scored three runs as the White Sox won for just the second time in eight games.
Matt Lindstrom (1-0) got one out for the win and Addison Reed finished for his fifth save in as many opportunities.
Edwin Encarnacion and Adam Lind hit consecutive singles off Reed to begin the ninth, just the second and third hits he's allowed this season. Brett Lawrie followed with a sacrifice fly, but Reed got Rajai Davis and Maicer Izturis to fly out.
Colby Rasmus and J.P. Arencibia hit solo home runs for the Blue Jays, who couldn't hold on after taking a 2-1 lead in the sixth.
Facing reliever Steve Delabar, Adam Dunn walked to begin the ninth and was replaced by pinch runner Dewayne Wise. Konerko followed with a walk and Conor Gillaspie struck out before Viciedo drove in Wise with a double over the head of center fielder Emilio Bonifacio.
Alexei Ramirez was intentionally walked and Darren Oliver came on to face Hector Gimenez, who drove in Konerko with a sacrifice fly to right. Konerko slid home safely when the throw from Davis missed wide.
Delabar (1-1) allowed two runs and one hit in 1 1-3 innings.
The White Sox opened the scoring in the second, loading the bases with two singles and a walk before Konerko scored from third on a wild pitch by Blue Jays right-hander Josh Johnson.
Rasmus tied it in the bottom half with a two-out blast to center, his fourth.
Arencibia put the Blue Jays in front with a two-out homer in the sixth, his fifth of the season and second in two days.
Johnson had retired 10 straight White Sox batters but his streak ended quickly in the seventh as he fell behind 3-0 on Konerko before allowing a game-tying homer to left. For Konerko, the drive was his third.
Neither starter figured in the decision. Chicago's Dylan Axelrod allowed two runs and seven hits in six innings, walked one and struck out four. Johnson allowed two runs and four hits in a season-high seven innings. He walked two and struck out eight, also a season high.
Lawrie made his first start of the season after being activated off the 15-day disabled list Monday. Lawrie had been sidelined since early March with a strained left ribcage muscle suffered at the World Baseball Classic.
Blue Jays slugger Jose Bautista was held out of the starting lineup for the second straight game suffering from a sore back and flulike symptoms.
NOTES: Blue Jays LHP Ricky Romero threw a simulated game at extended spring training Tuesday, but is still not scheduled to appear in a minor league game. Toronto's opening day starter in 2012, Romero was optioned to Class A Dunedin near the end of spring training. ... Chicago pitching coach Don Cooper, who has been away while recovering from an illness, is set to rejoin the team Friday when the White Sox return to host the Minnesota Twins.