Achraf Yacoubou hit the tiebreaking 3-pointer late in the second half to help Villanova upset No. 5 Louisville 73-64 on Tuesday night.
The Wildcats (12-7, 3-3 Big East) led by as many as 10 points in the first half and rallied late in the second to send the Cardinals to their second straight loss. Louisville (16-3, 4-2) had an 11-game winning streak end in a 70-68 loss to Syracuse on Saturday.
Ryan Arcidiacono scored 15 points, and JayVaughn Pinkston and Mouphtaou Yarou each scored 11 for Villanova.
The Wildcats students packed behind each basket stormed the court in a wild celebration for a win coach Jay Wright's struggling program badly needed.
Yacoubou hit the go-ahead 3 with just less than 4 minutes left and the Wildcats held on from there.