Leonard Washington had 14 points and 14 rebounds to help Wyoming beat a cold shooting No. 15 San Diego State 58-45 on Saturday night.
Larry Nance Jr. added 11 points and 12 rebounds, and Derrious Gilmore had 13 points for the Cowboys (15-2, 2-2 Mountain West).
Wyoming's win snapped a five-game losing streak to the Aztecs.
SDSU (14-4, 2-2) lost its second game in a row, the first time this season the Aztecs have lost back-to-back games. SDSU fell to UNLV on Wednesday.
Jamaal Franklin led SDSU with 13 points — 5 points below his season average.
The Aztecs, who entered the game averaging 72 points, struggled from the field Saturday night. They hit just 29 percent (17-of-59), making just 2-of-18 3-point attempts. The 45 total points was the lowest of the season, second only to the 49 SDSU scored in its first game of the season — a loss to Syracuse on an outdoor court.
SDSU scored just 9 points in the first half on four field goals and a free throw. It was its lowest point total for a half this season.
However, Wyoming wasn't much better in the first half, keeping San Diego State in the game with its own shooting woes — making just 8-of-25 shots — for a 20-9 halftime lead.
Both teams improved their shooting in the second half, but SDSU was never able to mount a serious challenge, getting no closer than 52-41with 1:33 left in the game.
Wyoming ended the game shooting 43 percent from the floor (18-42) and made 4-of-16 3-pointers.
SDSU played without starting guard Xavier Thames, who sat out the game because of a recurring back injury.
Winston Shepard, a highly recruited 6-8 freshman from Houston, made his second start in replacing Thames and finished with 10 points.