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Potential therapeutic target for tobacco-related lung cancers identified Researchers have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers.
Tobacco carcinogens induce IKBKE and, in turn, IKBKE induces chemotherapy resistance.
"IKBKE is a newly identified oconogene, a gene linked to cancer," said study lead author Jin Q. Cheng, Ph.D., M.D., who studies genetic alterations and their
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